Pneumocystis jirovecii pneumonie (PJP)
Advices
| Priority | Medication | Remarks |
|---|---|---|
|
Priority: 1st choice |
Medication: cotrimoxazol (trimethoprim + sulfamethoxazol) po 1920mg 3dd 21 days |
Remarks:
Bij gewicht <50 kg dosering 1440mg |
|
Priority: 2nd choice |
Medication: clindamycine po 600mg 3dd 21 days +
primaquine po 30mg 1dd 21 days |
Remarks:
bij overgevoeligheid cotrimoxazol (primaquine niet toedienen bij glucose-6-fosfaat dehydrogenase (G6PD) deficientie) |
|
Priority: 2nd choice alternative |
Medication: trimethoprim po 300mg 3dd 21 days +
dapsone po 100mg 1dd 21 days |
Remarks:
bij overgevoeligheid cotrimoxazol |
|
Priority: 3rd choice |
Medication: atovaquon po 750mg 2dd 21 days |
Remarks:
suspensie, innemen met voedsel |
| Priority | Medication | Remarks |
|---|---|---|
|
Priority: 1st choice |
Medication: cotrimoxazol (trimethoprim + sulfamethoxazol) iv 1920mg 3dd 21 days |
|
|
Priority: 2nd choice |
Medication: clindamycine iv 600mg 3dd 21 days +
primaquine po 30mg 1dd 21 days |
Remarks:
of 3dd 600mg po |
|
Priority: 3rd choice |
Medication: pentamidine iv 4mg/kg 1dd 21 days |
Sources
-
https://clinicalinfo.hiv.gov/en/guidelines/hiv-clinical-guidelines-adult-and-adolescent-opportunistic-infections/pneumocystis-0?view=full
Richtlijnen Ned. Ver. van HIV behandelaars (NVHB)
Antimicrobial resources
The following antimicrobial agents have been used in these recommendations:
External antimicrobial resources
Menu position
Metadata
Swab vid: G-502001.1
Updated: 12/19/2023 - 19:26
Status: Published
General comments
Bij pO2 < 70 mm Hg of < 9 kPa toevoegen prednison:
dag 1-5 2 dd 40 mg;
dag 6-10 2 dd 20 mg;
dag 11-14 1 dd 20 mg
Na behandeling secundaire profylaxe